If you’re looking for a quick and delicious weeknight dinner, our Mayo Parmesan Chicken is your perfect fix. This flavor-packed dish combines juicy chicken breasts with creamy mayonnaise and savory Parmesan cheese, creating a dinner triumph that’s irresistible and ready in under 30 minutes.
Growing up, my family looked forward to weekends, not for the break from school or work, but for my mom’s special Chicken Recipe. She would effortlessly whip it up, and the house would be filled with heavenly aromas. The secret, she’d say with a wink, is in the mayonnaise. Now, watching my own children devour it with just as much enthusiasm, I know this recipe is a legacy worth continuing.
Why You’ll Love This Recipe
There are countless reasons to fall in love with this dish. First, it’s incredibly easy to prepare, making it ideal for busy weeknights. The combination of mayonnaise and Parmesan ensures each bite is moist and full of flavor, while the simple seasoning elevates these flavors to gourmet levels. Plus, mayo acts as a tenderizer, ensuring the chicken is perfectly juicy every time. Best of all, this dish doubles up as a family-pleaser and a dinner-party delight.
Ingredients Notes
To make this dish, you’ll need chicken breasts, mayonnaise, Parmesan cheese, garlic powder, salt, and pepper. For the best flavor, opt for freshly grated Parmesan cheese. If you don’t have chicken breasts on hand, chicken thighs make a great alternative. Ensure your chicken is at room temperature before starting the preparation for even cooking.
Recipe Steps
Step 1
Preheat your oven to 400°F (200°C). Line a baking dish with parchment paper or lightly grease it with cooking spray to prevent sticking.
Step 2
In a small bowl, mix mayonnaise, grated Parmesan, garlic powder, salt, and pepper. Stir until combined into a smooth paste.
Step 3
Lay chicken breasts in the prepared baking dish in a single layer. Evenly spread the mayonnaise mixture over each piece, ensuring full coverage.
Step 4
Bake in the preheated oven for 20-25 minutes or until the chicken is fully cooked through and the top is golden and bubbly.
Step 5
Remove the chicken from the oven and let it rest for a few minutes before serving. This helps retain the juices and ensures maximum tenderness.
Storage Options
Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place in a preheated oven until warmed through for the best results. If you’d like to freeze this dish, wrap each piece individually in foil and place them in a freezer-safe bag. Reheat from frozen at a lower temperature to ensure even warming.
Variations & Substitutions
If you’re looking to mix things up, try adding herbs like rosemary or thyme to the mayo mixture for a more aromatic twist. For those preferring a healthier version, substitute regular mayo with Greek yogurt. Vegetarians can swap chicken for thick slices of eggplant or zucchini, which work beautifully with the creamy topping.
Serving Suggestions
This dish pairs perfectly with a side of steamed vegetables, a crisp green salad, or buttery mashed potatoes. Ideal for a cozy weeknight dinner, it’s also sophisticated enough for a dinner party spread. For a delightful weekend brunch, try serving it alongside a cheesy frittata or fluffy pancakes.
Frequently Asked Questions
Can I use low-fat mayonnaise?
Yes, low-fat mayonnaise can be used, though the full-fat version creates a richer and creamier texture. You may find the low-fat variant doesn’t coat as well but it remains a suitable substitute.
How do I know when the chicken is done?
Using a meat thermometer is the most reliable way to ensure chicken is safely cooked. The internal temperature should reach 165°F (75°C) to be sure it’s done. The juices running clear and the meat no longer being pink are also good indicators.
What can I do with leftover mayonnaise mixture?
If you have leftover mixture, consider using it as a sandwich spread, a base for a potato salad, or a flavorful dip for fresh vegetables. It will keep well in a tightly-sealed container in the refrigerator for up to a week.

Mayo Parmesan Chicken
Ingredients
Main Ingredients
- 4 pieces chicken breast boneless and skinless
- 1 cup mayonnaise
- 1 cup grated Parmesan cheese
- 0.5 tsp garlic powder
Instructions
Preparation Steps
- Preheat oven to 375°F (190°C) and place chicken breasts in a baking dish.
- Mix mayonnaise, Parmesan, and garlic powder in a bowl.
- Spread the mixture evenly over the chicken.
- Bake for 25 minutes or until chicken is cooked through and the topping is golden brown.