In a large bowl, combine ground beef, ground pork, breadcrumbs, milk, onion, garlic, salt, pepper, and Worcestershire sauce. Mix gently until just combined.
In a small bowl, combine ketchup, brown sugar, and vinegar.
Shape the meat mixture into a loaf and place it in a loaf pan.
Spread the ketchup mixture over the top of the meatloaf.
Bake for 60 minutes, or until a meat thermometer inserted into the center registers 160°F (71°C).
Let rest for 10 minutes before slicing and serving.
Notes
Serve with mashed potatoes and your favorite vegetables!